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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
12.5 DPC

15 matching records from 15 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hoxc8  homeobox C8   (Synonyms: D130011F21Rik, Hox-3.1)
Results  Reference
1*J:32906 Awgulewitsch A, Jacobs D, Differential expression of Hox 3.1 protein in subregions of the embryonic and adult spinal cord. Development. 1990 Mar;108(3):411-20
1*J:49697 Belting HG, Shashikant CS, Ruddle FH, Multiple phases of expression and regulation of mouse Hoxc8 during early embryogenesis. J Exp Zool. 1998 Sep-Oct 1;282(1-2):196-222
1J:227707 Carroll LS, Capecchi MR, Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/beta-catenin signaling. Development. 2015 Dec 1;142(23):4056-67
1J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
1J:277959 Catela C, Shin MM, Lee DH, Liu JP, Dasen JS, Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfralpha Genes. Cell Rep. 2016 Mar 1;14(8):1901-15
1J:253351 Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS, Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
1J:166088 Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS, Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010 Sep 9;67(5):781-96
1J:195163 Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein J, Dasen JS, Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013 Jan;9(1):e1003184
1J:244791 Li CJ, Hong T, Tung YT, Yen YP, Hsu HC, Lu YL, Chang M, Nie Q, Chen JA, MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord. Nat Commun. 2017 Mar 24;8:14685
1J:119016 Liu JP, The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord. Development. 2006 Aug;133(15):2865-74
1J:256105 Mendelsohn AI, Dasen JS, Jessell TM, Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles. Neuron. 2017 Feb 22;93(4):792-805.e4
1J:197494 Philippidou P, Walsh CM, Aubin J, Jeannotte L, Dasen JS, Sustained Hox5 gene activity is required for respiratory motor neuron development. Nat Neurosci. 2012 Dec;15(12):1636-44
1*J:35249 Sreenath TL, Pollock RA, Bieberich CJ, Functional specificity of Hoxa-4 in vertebral patterning lies outside of the homeodomain. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9636-40
1*J:45780 Tiret L, Le Mouellic H, Maury M, Brulet P, Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice. Development. 1998 Jan;125(2):279-91
1*J:14430 Tomotsune D, Shoji H, Wakamatsu Y, Kondoh H, Takahashi N, A mouse homologue of the Drosophila tumour-suppressor gene l(2)gl controlled by Hox-C8 in vivo. Nature. 1993 Sep 2;365(6441):69-72

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory